Transperineal Prostate Biopsy in Knoxville, TN

At University Urology, our fellowship-trained urologic oncologists provide the most advanced options for diagnosing prostate cancer. One of the safest and most accurate techniques available today is the transperineal prostate biopsy. Unlike traditional transrectal biopsies, this method offers greater precision and significantly lowers the risk of infection.

Why Choose a Transperineal Biopsy?

  • Lower Infection Risk – Needle passes through the perineal skin instead of the rectum, greatly reducing infection risk.
  • More Accurate Sampling – For certain patients, Better access to the anterior and apex of the prostate, where cancers may hide.
  • Outpatient Procedure – All patients go home the same day.
  • Improved Comfort – Performed with under sedation.

Who Needs a Prostate Biopsy?

Your urologist may recommend a biopsy if you have:

  • Elevated PSA (Prostate-Specific Antigen) blood test
  • Abnormal digital rectal exam (DRE)
  • Suspicious area on prostate MRI
  • Family history or genetic risk of prostate cancer

What to Expect

  1. Preparation: Usually no antibiotics are required due to very low infection risk.
  2. Anesthesia: Typically light sedation.
  3. Procedure: Ultrasound guidance is used to take small tissue samples through the perineum.
  4. Recovery: Most patients return to normal activity within 1–2 days.

Why University Urology?

  • Regional Leaders: Fellowship-trained urologic oncologists with expertise in prostate cancer diagnosis and treatment.
  • Advanced Imaging: MRI/ultrasound fusion biopsy technology available.
  • Comprehensive Cancer Care: All prostate cancer treatment options in one center.
  • Patient-Centered: We provide guidance and support every step of the way.

Frequently Asked Questions

Is a transperineal biopsy painful?

Most patients report minimal discomfort with anesthesia.

What are the risks?

Temporary blood in urine or semen is common. The risk of infection is extremely low compared to transrectal biopsy.

How long does it take?

The procedure typically takes 20–30 minutes.

Will insurance cover it?

Yes. Most insurance plans cover prostate biopsies when medically indicated.

If you or a loved one has an elevated PSA or suspicious MRI, ask about a transperineal prostate biopsy at University Urology in Knoxville, Tennessee.

📞 Call Us: 865.305.9254
📍 Visit Us: Multiple locations across East Tennessee